一、履历

kaiyun体育官方网站医学院讲师。2011年本科毕业于河南科技大学，2014年硕士毕业于华中农业大学，2019年博士毕业于中国科学院武汉病毒研究所。

二、研究方向

1. 以黄病毒、冠状病毒为代表的RNA病毒快速检测方法和试剂研发；2. RNA病毒新型疫苗的研发与评价；3. 重要RNA病毒感染与宿主互作的分子机制。

三、主要科研成果

作为主研人参与国家自然科学基金4项，其中已结题3项。

四、代表性论文

1.  Li Penghui ^#, Yao C^#, Wang  T, Wu T, Yi W, Zheng Y, Miao Y, Sun J, Tan Z, Liu Y, Zhang X, Wang H, Zheng Z. Recovery of a Far-Eastern Strain of Tick-Borne Encephalitis Virus with a Full-Length Infectious cDNA Clone. Virologica Sinica. 2021. Doi:10.1007/s12250-021-00396-6. Online ahead of print.

2.  Wang T ^#, Li Penghui ^#, Zhang Y, Liu Y, Tan Z, Sun J, Ke X, Miao Y, Luo L, Hu Q, Xu F, Wang H, Zheng Z. In vivo imaging of Zika virus reveals dynamics of viral invasion in immune-sheltered tissues and vertical propagation during pregnancy. Theranostics. 2020. 10: 6430-6447.

3.  Li Penghui, Ke X, Wang T, Tan Z, Luo D, Miao Y, Sun J, Zhang Y, Liu Y, Hu Q, Xu F, Wang H, Zheng Z. ZIKA Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models. Journal of Virology. 2018. 92:e00701-18.

4.  Li Penghui, Zheng P, Zhang T, Wen G, Shao H, Luo Q. Fowl adenovirus serotype 4: Epidemiology, pathogenesis, diagnostic detection, and vaccine strategies. Poultry Science. 2017. 96:2630-2640.

6.  Luo D, Miao Y, Ke X, Tan Z, Hu C, Li Penghui, Wang T, Zhang Y, Sun J, Liu Y, Wang H, Zheng Z. 2020. Baculovirus Surface Display of Zika Virus Envelope Protein Protects against Virus Challenge in Mouse Model. Virologica Sinica. 2020. 35(5):637-650.

5.  Sun J, Zhang W, Tan Z, Zheng C, Tang Y, Ke X, Zhang Y, Liu Y, Li Penghui, Hu Q, Wang H, Mao P, Zheng Z. Zika virus promotes CCN1 expression via the CaMKIIα-CREB pathway in astrocytes. Virulence. 2020. 11: 113-131.

7.  Deng C, Liu S, Zhou D, Xu L, Li X, Zhang P, Li Penghui, Ye H, Wei H, Yuan Z, Qin C, Zhang B. Development of Neutralization Assay Using an eGFP Chikungunya Virus. Viruses. 2016. 28;8(7):181.

8.  Tan Z, Zhang W, Sun J, Fu Z, Ke X, Zheng C, Zhang Y, Li Penghui, Liu Y, Hu Q, Wang H, Zheng Z. ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells. Journal of neuroinflammation. 2018. 15:275.

9.  Tian Z, Yang L, Li Penghui, Xiao Y, Peng J, Wang X, Li Z, Liu M, Bi D, Shi D. The inflammation regulation effects of Enterococcus faecium HDRsEf1 on human enterocyte-like HT-29 cells. Animal Cells and Systems. 2016. 20:70-76.

五、联系方式

Email: lipenghui101@126.com